https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4344 Wed 11 Apr 2018 16:10:23 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:10454 0.05). Median admission plasma-paraquat concentration in patients with peripheral burning (2.67 μg/mL, 95% CI = 0.84–14.2) was significantly higher than in the patients with no peripheral burning (0.022 μg/mL, 95% CI = 0.005–0.78; p < 0.001). Peripheral burning has a sensitivity of 0.72 (95% CI = 0.6–8) and specificity of 0.74 (95% CI = 0.64–0.08) and a positive predictive value of 0.73 (95% CI = 0.6–0.8). Discussion: It is possible that this symptom may help discriminate between patients who have poor chance of survival and those who may potentially benefit from interventions. The mechanism is not clear but could either include a direct concentration-related effect or be a marker of oxidative stress. Conclusion: Presence of burning sensation is associated with high plasma-paraquat concentrations and is strongly predictive of death.]]> Sat 24 Mar 2018 08:08:02 AEDT ]]>